Ageless and Outrageous

Podcast by Kristin Jackson

Ageless and Outrageous

Welcome to "Ageless & Outrageous", the podcast where urogynecologist and hormone and sexual health expert, Dr. Kristin Jackson, shares her 25 years of expertise to guide both men and women on the path to aging amazingly. Listen as she dives into a spectrum of topics, with an emphasis on hormone optimization, pelvic floor health, and maintaining vibrant sexual experiences as we age. From exploring the intricacies of hormonal balance to discussing strategies for pelvic floor well-being, Dr. Jackson brings you real-life insights rooted in solid scientific knowledge. Get ready for a podcast that combines the wisdom of years of medical practice with an approach that's relatable and enjoyable. Tune in for a dose of laughter, knowledge, and a rejuvenated perspective on the incredible adventure of growing older.

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Latest episodes

12 June 2025

Estrogen Is Everywhere: What They Didn’t Tell You About Menopause

Most people associate estrogen loss with hot flashes and night sweats, but the truth is—estrogen affects nearly every part of the body. I often see women struggling with fatigue, brain fog, bladder irritation, joint pain, and sleep problems, and they’ve never been told these symptoms could be related to perimenopause or menopause. In this episode, I walk through the science of how estrogen functions in different tissues and share real examples from three patients in their 40s, 50s, and 70s—all experiencing very different symptoms tied to the same hormonal shift.

We have to move beyond the idea that menopause only affects the ovaries. When estrogen drops, the brain, bones, muscles, skin, and bladder all feel it—and understanding this opens the door to smarter, more personalized treatment.

You NEED to know:

Why estrogen loss doesn’t always present as hot flashes
The musculoskeletal syndrome of menopause: how estrogen protects joints and muscle
How low estrogen disrupts sleep, mood, memory, and concentration
The role of estrogen in preserving bone mass and preventing fractures
Genitourinary syndrome of menopause (GSM): what happens to the vagina and bladder
Why women can still have low estrogen symptoms even with regular periods
Limitations of hormone blood tests in your 40s
How I approach estrogen therapy in women in their 40s, 50s, and 70s
What vaginal estrogen does (and why it doesn’t increase cancer risk)
Why estrogen is essential—not optional—for aging well

Estrogen does so much more than regulate the menstrual cycle—it influences everything from our joints to our mood to our ability to sleep soundly at night. Understanding how deeply this hormone impacts the entire body is the first step toward reclaiming wellness during perimenopause, menopause, and beyond. Whether symptoms show up subtly or dramatically, they deserve to be taken seriously. With the right evaluation and a personalized treatment plan, it's possible to feel strong, clear, and supported again—at any age.

Read Dr J's blog to find out why personalized hormone replacement is best: https://www.foundationsfl.com/post/precise-personalized-menopausal-hormone-therapy

And you can learn more about all thing hormone replacement here: https://www.foundationsfl.com/bioidentical-hormone-optimization

Instagram https://www.instagram.com/foundationskristinjacksonmd/

Website https://www.foundationsfl.com/

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26:46

05 June 2025

Sermorelin: The Secret to Muscle, Sleep, and Longevity?

In this episode of Ageless and Outrageous, I dive into one of my favorite add-ons for optimizing weight loss, improving recovery, and aging better: Sermorelin. While often confused with growth hormone itself, Sermorelin works upstream—by signaling your pituitary to produce more of your own natural growth hormone. It’s one of the most exciting ways to maintain muscle, reduce visceral fat, and support vibrant aging without shutting down your hormone system.

If you’re doing everything right—strength training, eating protein, balancing your hormones—but still feel like something’s missing, Sermorelin might be the next step.

🔍 Listen in to learn:

What Sermorelin is and how it differs from synthetic growth hormone
How Sermorelin supports muscle growth, bone health, and visceral fat reduction
Why growth hormone production naturally declines with age
Benefits beyond body composition: improved sleep, mood, skin elasticity, and immune function
Why Sermorelin is a safer alternative to direct growth hormone therapy
Proper dosing protocols and why it mimics the body’s natural rhythm
Important precautions: cancer screenings, thyroid health, and IGF-1 monitoring
How Sermorelin can complement your weight loss or HRT program for stronger results

Whether you're working to lose weight, maintain muscle, improve your sleep, or simply feel more vibrant as you age, Sermorelin offers a powerful, science-backed tool to support your goals. It’s not a magic bullet, but when paired with resistance training, optimal protein intake, and balanced hormones, it can take your results to the next level. As always, it’s important to work with a qualified provider to ensure safe and effective use. If you’ve been looking for a way to rebuild from the inside out—Sermorelin might just be the boost your body has been waiting for.

Read Dr J's blog on Sermorelin injections here: https://www.foundationsfl.com/post/sermorelin-could-be-your-secret-weight-loss-weapon

Instagram https://www.instagram.com/foundationskristinjacksonmd/

Website https://www.foundationsfl.com/

FB facebook.com/advancedurogynecology

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16:50

27 May 2025

Testosterone & Mood: What the Research Really Shows

Let's review a powerful new study on how testosterone therapy can improve mood, cognition, and libido in perimenopausal and menopausal women—even those already on hormone replacement therapy. If you've been struggling with brain fog, irritability, or a loss of motivation and joy, this episode offers a science-backed look at one often-overlooked solution.

Here’s what you’ll discover:

🧪 The results of a large study tracking 510 women who added testosterone to their HRT
🔄 Why common mood and cognitive symptoms may not be “just stress” or “just aging”
💥 A 47% improvement in mood and 52% boost in libido after only four months
🧠 The surprising link between testosterone and brain function in women
🚫 Why the “testosterone is only for men” myth needs to go
🧾 What it means when a treatment is off-label—and why that’s more common than you think
🩺 How I uses testosterone in her practice and what to consider if your current regimen isn’t working
💬 Tools to better describe and track your symptoms, so you can advocate for yourself confidently

Whether you’re already on hormone therapy or just starting to explore options, this episode offers a fresh, practical perspective on what testosterone could do for your quality of life. If you’ve been feeling unlike yourself lately—this conversation might be the missing piece.

Learn more about bioidentical hormone replacement here:

https://www.foundationsfl.com/testosterone-pellet-therapy-orlando

Instagram https://www.instagram.com/foundationskristinjacksonmd/

Website https://www.foundationsfl.com/

FB facebook.com/advancedurogynecology

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20:37

20 May 2025

Big News on Treating GSM! The 2025 Update You Need to Hear

In this timely episode, I am excited to share the brand-new 2025 clinical guidelines for treating Genitourinary Syndrome of Menopause (GSM)—a long-overdue update that prioritizes shared decision making and patient-centered care. Whether you’re a patient navigating vaginal dryness, bladder issues, or recurrent UTIs, or a clinician looking to stay current, this episode is a must-listen. We'll go over the science, dispel myths about estrogen safety, and learn how these guidelines shift the conversation around midlife women’s health.

What you’ll learn in this episode:

💡 Why the new GSM guidelines are revolutionary—and long overdue
🧠 What shared decision making really means in patient care
🌸 The real truth about vaginal estrogen safety (yes, even for breast cancer survivors)
🔍 How low hormones—estrogen AND testosterone—cause GSM symptoms
🧴 Treatment options beyond estrogen: DHEA, Ospemifene, and vaginal testosterone
🚽 How vaginal estrogen reduces bladder symptoms and cuts recurrent UTIs by 52%
🧬 Why package inserts are misleading—and how FDA labeling has confused patients for years
📢 A call to action for both providers and patients: know your options and advocate for your quality of life

This episode is a critical listen for both patients and providers alike. Whether you're experiencing GSM symptoms yourself or helping women manage this often-overlooked condition, the insights and updates shared here are essential for making empowered, evidence-based decisions.

Instagram https://www.instagram.com/foundationskristinjacksonmd/

Website https://www.foundationsfl.com/

FB facebook.com/advancedurogynecology

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26:55

05 March 2025

The Mind-Body Connection: Optimizing Wellness with Dr. Christine Vaccaro

In this episode, I sit down with Dr. Christine Vaccaro to dive into the powerful connection between mindset, hormones, and overall well-being. Dr. Vaccaro shares her approach to integrative medicine, emphasizing how lifestyle choices, stress management, and personalized hormone optimization play a crucial role in longevity and quality of life. We explore how women can take control of their health by addressing both physical and emotional well-being.

Join us as we discuss:

How stress and mindset directly impact hormonal balance and overall health
Why personalized hormone therapy can be a game-changer for energy, mood, and longevity
The critical role of gut health in inflammation and disease prevention
Why conventional medicine often overlooks lifestyle factors in patient care
Simple, actionable strategies to improve wellness, from nutrition to mindfulness practices

If you’re ready to take a proactive approach to your health and feel your best at any age, this episode is packed with valuable insights and practical tips! 🎧✨

Dr Christine Vaccaro is a double board certified and fellowship trained urogynecologist and sexual medicine specialist, who has been in practice for over 20 years. She is an associate professor of gynecologic surgery at the Uniformed Services University in Bethesda. She recently retired from the military, and was the Program Director for the Urogynecology Fellowship at Walter Reed, and now practices at the offices of Rachel Rubin, MD, located in Bethesda, MD.

She is also involved in multiple national medical committees, and has extensively published in medical journals, medical textbooks and online. She is medical advisor for the SHE+ (Sexual Health Education PLUS) Foundation, which is a non-profit organization which supports women's sexual health through research, education, advocacy and grant funding. When not at work she enjoys hot yoga and attending her kid's sporting events.

Social Media & Links:

Instagram: @drchristinevaccaro

Linktr.ee: linktr.ee/drchristinevaccaro

Practice website: https://www.rachelrubinmd.com/

YouTube (practice): youtube.com/@DrRachelRubin

Thank you to Dr Vaccaro for this incredible episode!

Instagram https://www.instagram.com/foundationskristinjacksonmd/

Website https://www.foundationsfl.com/

FB facebook.com/advancedurogynecology

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56:54

26 February 2025

The Truth About Hormone Replacement with Dr. Amy Killen

In this must-listen episode, I'm speaking with Dr. Amy Killen, a leading expert in hormone optimization and longevity medicine. Dr. Killen shares her journey from emergency medicine to preventive care, driven by the realization that our healthcare system often fails to keep people truly healthy. Together, we unravel the science behind hormone replacement therapy (HRT), debunk common fears surrounding estrogen and breast cancer, and discuss why bioidentical hormones matter.

Join us as we dive into:

The difference between bioidentical and synthetic hormones—and why it matters
Why most doctors aren’t trained in menopause medicine and how women can advocate for better care
The real risks and benefits of hormone therapy, including its impact on heart, brain, and bone health
How estrogen plays a critical role in everything from skin hydration to preventing osteoporosis
Why hormone balance is a key factor in longevity and aging well

If you’ve ever had questions about hormone therapy, this episode delivers science-backed answers that every woman needs to hear! 🎧✨

Dr. Amy B. Killen, M.D. is a leading physician in regenerative and hormone optimization medicine, specializing in women's health and helping patients navigate their "Queen Phase™" with evidence-based interventions. A board-certified emergency physician turned longevity specialist, she combines cutting-edge treatments like stem cell therapy, hormone optimization, and peptides with practical lifestyle wisdom at her Utah and Texas clinics while sharing her expertise through international speaking engagements and educational content creation.

As Chief Medical Officer of Humanaut Health and founder of the Human Optimization Project (HOP), Dr. Killen continues to advance the field of longevity medicine with her "(r)Age Against the Mainstream" approach.

She lives in Salt Lake City with her family of five.

Follow Dr Killen on social:

IG/FB: @dr.amybkillen, @hopboxlife , @humanauthealth

Twitter: KillenMD

Websites: www.dramykillen.com, www.humanauthealth.com, www.hopbox.life

Thank you Dr Killen for your wonderful insights!

Instagram https://www.instagram.com/foundationskristinjacksonmd/

Website https://www.foundationsfl.com/

FB facebook.com/advancedurogynecology

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52:22