The Forgotten Hormone: Why DHEA Might Be Your Missing Piece

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DHEA is one of the most overlooked hormones in the conversation around aging well, but it plays a powerful role in energy, mood, metabolism, and muscle maintenance. I often see patients who are doing everything right—eating clean, sleeping well, on hormone replacement—but still feel like something is missing. That something could be DHEA.

This hormone starts declining in your 30s and 40s, and without it, your body may struggle to produce testosterone, estrogen, and critical immune and brain chemicals. In this episode, I explain how DHEA works, how to know if you’re low, and how to safely supplement it if needed.

Do you want to understand:

What DHEA is and how it differs from other sex hormones
Why DHEA levels start declining as early as your 30s
Symptoms of low DHEA: fatigue, belly fat, low libido, poor muscle tone
How DHEA supports bone growth, immune health, metabolism, and mood
The connection between DHEA and cortisol (stress hormone)
Best practices for testing and ideal blood level targets
Over-the-counter vs. compounded supplements: what to watch out for
DHEA’s use in vaginal health (including Intrarosa and compounded options)
Common misconceptions about hair loss and DHEA
When to consider DHEA as part of a broader HRT strategy

DHEA may not get the attention that estrogen and testosterone do, but it’s a foundational hormone that supports multiple systems in the body. From energy and fat metabolism to mood and immune defense, low DHEA can quietly affect how you feel, look, and function. Supplementing—when guided by lab testing and clinical signs—can help fill in the hormonal gaps and bring new vitality to your day-to-day life. With the right dose and delivery method, it might just be the missing link in your longevity and wellness plan.

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